California Is at It Again!

Play it again, Sam--depression is recurring.

Doing It Again and Again May Be Difficult, But It Depends on What You Are Doing

Sentence interpretation is integrating the information of incoming lexical items into a coherent whole. But often the pieces of information do not fit together and have to be shifted in meaning to confirm with the rest of the sentence. These shifts are called coercion (Moens & Steedman, 1988; Pustejovsky, 1995). There is a growing body of experimental work that investigates the processing conse...

Cardiovascular Biology: Play It Again, Gata4

To function properly, the vertebrate heart must navigate challenging periods by utilizing appropriate stress-response pathways. A new study highlights a crucial role for the transcription factor Gata4 in mediating diverse stress responses in the zebrafish heart.

Generating Media Stories – Play it again, Sam

New types of knowledge spaces, such as the web, allow for yet unexplored forms of knowledge exploration and social relationships. Such an interactive, open and multimodal system sustains the activation of articulation expressions that form the basis of adaptive discourses. In this paper we look at the problem of how stories in such environments can be established. We are in particular intereste...

Replication Licensing: Oops! … I Did It Again

All eukaryotes use multiple controls to restrict DNA replication to once per cell cycle. Nevertheless, inactivation of a single gene, cul-4, causes massive re-replication in Caenorhabditis elegans. A novel study explains this dramatic phenotype by demonstrating that the CUL-4 E3 ligase simultaneously controls two critical licensing factors: CDT-1 and CDC-6.